Piericidin A from microbial source

• 产品号: P4368
• CAS号: 2738-64-9
• 分子式: C25H37NO4
• 分子量: 415.56558
• 纯 度: >95% (HPLC)

产品别名

• 标题: Piericidin A from microbial source
• IUPAC标准名: 2-[(9R,10R)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-5,6-dimethoxy-3-methylpyridin-4-ol
• IUPAC传统名: 2-[(9R,10R)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-5,6-dimethoxy-3-methylpyridin-4-ol
• 别名: 4-Pyridinol,2-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-5,6-dimethoxy- [R-[R*,R*-(all-E)]]-3-methyl-; SN 198E; Piericidin A1; 2,6,9,11-Tridecatetraen-4-ol,13-(4-hydrox-5,6-dimethoxy-3-methyl-2-pyridyl)-3,5,7,11-tetramethyl-(all-E)-(4R,5R); Shaoguamycin B

产品登记号

• PubChem SID: 24898532
• MDL号: MFCD01677956
• CAS号: 2738-64-9

产品性质

• Empirical Formula (Hill Notation): C25H37NO4
• 纯度: >95% (HPLC)
• 运输包装: wet ice
• 外观: DMSO solution
• 闪点: 85 °C
• 闪点: 185 °F
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• 危险公开号: 20/21/22
• 安全公开号: 36/37
• 保存温度: 2-8°C
• 德国WGK号: 1

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Piericidin A is a potent inhibitor of the mitochondrial and bacterial type I NADH-ubiquinone oxireductase (Complex I). It is considered to bind to the ubiquinone binding sites of the enzyme. Peiricidin A inactivation of complex I completely prevents NADH-induced proton translocation in the NADH-endogenous ubiquinone reductase reaction.

详细说明 (简体中文)

Biochem/physiol Actions
Piericidin A is a potent inhibitor of the mitochondrial and bacterial type I NADH-ubiquinone oxireductase (Complex I). It is considered to bind to the ubiquinone binding sites of the enzyme. Peiricidin A inactivation of complex I completely prevents NADH-induced proton translocation in the NADH-endogenous ubiquinone reductase reaction.