氯四环素 盐酸盐

• 产品号: 26430
• CAS号: 64-72-2
• 分子式: C22H24Cl2N2O8
• 分子量: 515.34056
• 纯 度: ≥97.0% (AT)

产品别名

• 标题: Chlortetracycline hydrochloride
• IUPAC标准名: (4S,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
• IUPAC传统名: aureomycin hydrochloride
• 别名: 7-Chlorotetracycline hydrochloride; 金霉素 盐酸盐

产品登记号

• MDL号: MFCD00082440
• Beilstein号: 3858364
• CAS号: 64-72-2
• EC号: 200-591-7
• PubChem SID: 24856004

产品性质

• 生物来源: from Streptomyces aureofaciens
• Empirical Formula (Hill Notation): C22H23ClN2O8 · HCl
• 杂质: ≤3% water
• 产品线: BioReagent
• 纯度: ≥97.0% (AT)
• 适用性: suitable for fluorescence
• 荧光: λex 392 nm; λem 536 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+
• 熔点: 210-215 °C (dec.)(lit.)
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• RTECS编号: QI7800000
• 安全公开号: 26
• 保存温度: -20°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Application
Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions
Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.
Quality
Recommended for fluorescent studies of calcium signaling in cells or tissues.

详细说明 (简体中文)

Application
Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions
Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.
Quality
Recommended for fluorescent studies of calcium signaling in cells or tissues.