L-羟基脯氨酸

• 产品号: 56250
• CAS号: 51-35-4
• 分子式: C5H9NO3
• 分子量: 131.12986
• 纯 度: ≥99.0% (NT)

产品别名

• 标题: trans-4-Hydroxy-L-proline
• IUPAC标准名: (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
• IUPAC传统名: hypro
• 别名: (2S,4R)-4-羟基吡咯烷-2-羧酸; Hyp; (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid

产品登记号

• CAS号: 51-35-4
• EC号: 200-091-9
• PubChem SID: 24880041
• Beilstein号: 81441
• MDL号: MFCD00064320

产品性质

• 痕量阴离子: chloride (Cl-): ≤100 mg/kg
• 痕量阴离子: sulfate (SO42-): ≤100 mg/kg
• 痕量阳离子: Ca: ≤10 mg/kg
• 痕量阳离子: Cd: ≤5 mg/kg
• 痕量阳离子: Co: ≤5 mg/kg
• 痕量阳离子: Cr: ≤5 mg/kg
• 痕量阳离子: Cu: ≤5 mg/kg
• 痕量阳离子: Fe: ≤5 mg/kg
• 痕量阳离子: K: ≤50 mg/kg
• 痕量阳离子: Mg: ≤5 mg/kg
• 痕量阳离子: Mn: ≤5 mg/kg
• 痕量阳离子: NH4+: ≤100 mg/kg
• 痕量阳离子: Na: ≤50 mg/kg
• 痕量阳离子: Ni: ≤5 mg/kg
• 痕量阳离子: Pb: ≤5 mg/kg
• 痕量阳离子: Zn: ≤5 mg/kg
• Empirical Formula (Hill Notation): C5H9NO3
• 燃烧残渣: ≤0.1% (as SO4)
• 杂质: ≤0.3% foreign amino acids
• 干燥失重: ≤0.1% loss on drying, 110 °C
• 产品线: BioXtra
• 纯度: ≥99.0% (NT)
• 熔点: 273 °C (dec.)(lit.)
• 比旋光度: [α]20/D -76.0±1.5°, c = 5% in H2O
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Other Notes
Natural constituent of animal structural proteins such as collagen and elastin.
Enzymes and intermediates of hydroxyproline degradation1
Biochem/physiol Actions
Trans-4-Hydroxy-L-proline is used as a starting material in the synthesis of (-)-secrinine; the synthesis of prolinol-based nucleotide analogues with N-phosphonomethyl moiety attached to the nitrogen atom of prolinol ring and in asymmetric synthesis of the ABC-ring system of the antitumor antibiotic MPC1001.
Trans-4-Hydroxy-L-proline is used in the organic synthesis of depsilairdin analogues, noncompetitive peptidomimetic inhibitors of multidrug resistance P-glycoprotein and 3-guaninyl-5-hydroxymethyl-2-pyrrolidinone (4) or 3-adeninyl-5-hydroxymethyl-2-pyrrolidinone (5) nucleoside analogues.

详细说明 (简体中文)

Other Notes
动物结构蛋白（如胶原和弹性蛋白）的天然成分。
Enzymes and intermediates of hydroxyproline degradation1
Biochem/physiol Actions
Trans-4-Hydroxy-L-proline is used as a starting material in the synthesis of (-)-secrinine; the synthesis of prolinol-based nucleotide analogues with N-phosphonomethyl moiety attached to the nitrogen atom of prolinol ring and in asymmetric synthesis of the ABC-ring system of the antitumor antibiotic MPC1001.
Trans-4-Hydroxy-L-proline is used in the organic synthesis of depsilairdin analogues, noncompetitive peptidomimetic inhibitors of multidrug resistance P-glycoprotein and 3-guaninyl-5-hydroxymethyl-2-pyrrolidinone (4) or 3-adeninyl-5-hydroxymethyl-2-pyrrolidinone (5) nucleoside analogues.