Biochem/physiol Actions Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells. LPA, a bioactive lipid and a ligand for P2Y5 (a G protein-coupled receptor) , plays an importnt role in the maintenance of human hair growth 1. |