Cloxacillin sodium salt

• 产品号: 27555
• CAS号: 642-78-4
• 分子式: C19H17ClN3NaO5S
• 分子量: 457.86315
• 纯 度: ≥97.0% (HPLC)

产品别名

• 标题: Cloxacillin sodium salt
• IUPAC标准名: sodium (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• IUPAC传统名: sodium cloxacillin(1-)

产品登记号

• CAS号: 642-78-4
• EC号: 211-390-9
• PubChem SID: 24856654
• MDL号: MFCD00063568
• Beilstein号: 4103180

产品性质

• Empirical Formula (Hill Notation): C19H17ClN3NaO5S
• 杂质: ≤5% water
• 纯度: ≥97.0% (HPLC)
• 溶解度: H2O: soluble50 mg/mL, clear, colorless
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: XH8750000
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.
Application
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness1 and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria2.

详细说明 (简体中文)

Biochem/physiol Actions
Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.
Application
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness1 and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria2.