Antipain

• 产品号: 10791
• CAS号: 37691-11-5
• 分子式: C27H44N10O6
• 分子量: 604.70166

产品别名

• 标题: Antipain
• IUPAC标准名: (2S)-2-({[(1S)-4-carbamimidamido-1-{[(1S)-1-[(5-carbamimidamido-1-oxopentan-2-yl)carbamoyl]-2-methylpropyl]carbamoyl}butyl]carbamoyl}amino)-3-phenylpropanoic acid
• IUPAC传统名: (2S)-2-({[(1S)-4-carbamimidamido-1-{[(1S)-1-[(5-carbamimidamido-1-oxopentan-2-yl)carbamoyl]-2-methylpropyl]carbamoyl}butyl]carbamoyl}amino)-3-phenylpropanoic acid
• 别名: [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal

产品登记号

• EC号: 253-631-0
• Beilstein号: 6837629
• MDL号: MFCD00135959
• CAS号: 37691-11-5
• PubChem SID: 24846788

产品性质

• Empirical Formula (Hill Notation): C27H44N10O6
• GHS警示词: Warning
• GHS危险声明: H302
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: YV9350700
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Inhibits serine/cysteine proteases and some trypsin-like proteases. Compare activity to that of leupeptin. Used to evaluate the role of proteases in cell transformations. Used to help identify new proteases.
Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.1
Other Notes
Protease inhibitor2
Unit Definition
1 U corresponds to the amount of inhibitor which reduces the trypsin activity by 1 BAEE-U. (1 BAEE-U is the amount of enzyme which increases the absorbance at 253 nm by 0.001 per minute at pH 7.6 and 25°C; BAEE, Fluka No. 12880, as substrate)

详细说明 (简体中文)

Biochem/physiol Actions
Inhibits serine/cysteine proteases and some trypsin-like proteases. Compare activity to that of leupeptin. Used to evaluate the role of proteases in cell transformations. Used to help identify new proteases.
Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.1
Other Notes
Protease inhibitor2
Unit Definition
1 U corresponds to the amount of inhibitor which reduces the trypsin activity by 1 BAEE-U. (1 BAEE-U is the amount of enzyme which increases the absorbance at 253 nm by 0.001 per minute at pH 7.6 and 25°C; BAEE, Fluka No. 12880, as substrate)