Bis(2,2′-bipyridine)-(5-isothiocyanato-phenanthroline)ruthenium bis(hexafluorophosphate)

• 产品号: 71603
• CAS号: 288399-07-5
• 分子式: C33H23F12N7P2RuS
• 分子量: 940.6459804

产品别名

• 标题: Bis(2,2′-bipyridine)-(5-isothiocyanato-phenanthroline)ruthenium bis(hexafluorophosphate)
• IUPAC标准名: λ^2-ruthenium(2+) ion bis(2-(pyridin-2-yl)pyridine) 5-isothiocyanato-1,10-phenanthroline bis(hexafluoro-λ^5-phosphanuide)
• IUPAC传统名: λ^2-ruthenium(2+) ion 5-isothiocyanato-1,10-phenanthroline bis(bipyridyl) dihexafluorophosphate
• 别名: Ru(bpy)2(phen-5-isothiocyanate)(PF6)2

产品登记号

• CAS号: 288399-07-5
• MDL号: MFCD02683413
• PubChem SID: 24886230

产品性质

• Empirical Formula (Hill Notation): C33H23F12N7P2RuS
• 产品线: BioReagent
• 运输包装: dry ice
• 适用性: suitable for fluorescence
• 荧光: λex 445 nm; λem ~615 nm in 0.1 M phosphate pH 7.0
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Reactive probe containing fluorescent metal-ligand complex for determination of nucleotide base sequences.
Features and Benefits
Sigma-Aldrich offers a series of reactive dyes based on ruthenium complexes for use in fluorescence polarization assays and fluorescence lifetime imaging applications. They have been designed specifically to have long fluorescence lifetimes. These dyes were first synthesized in the labs of Dr. Joseph Lakowicz at the Center for Fluorescence Microscopy. These laser-excitable metal ligand complexes have fluorescence lifetimes near 500 nanoseconds. These dyes can be used to label amines on biomolecules under mild conditions. Advantages of these dyes as protein labels include high photostability, good water solubility, a lack of dye-dye interactions and large Stokes’ shifts. In addition, the fluorescence signal of long-lived fluorophores can be gated to eliminate the emission from short-lifetime fluorophores and autofluorescence from cells and biomolecules to further improve sensitivity.

详细说明 (简体中文)

Application
Reactive probe containing fluorescent metal-ligand complex for determination of nucleotide base sequences.
Features and Benefits
Sigma-Aldrich offers a series of reactive dyes based on ruthenium complexes for use in fluorescence polarization assays and fluorescence lifetime imaging applications. They have been designed specifically to have long fluorescence lifetimes. These dyes were first synthesized in the labs of Dr. Joseph Lakowicz at the Center for Fluorescence Microscopy. These laser-excitable metal ligand complexes have fluorescence lifetimes near 500 nanoseconds. These dyes can be used to label amines on biomolecules under mild conditions. Advantages of these dyes as protein labels include high photostability, good water solubility, a lack of dye-dye interactions and large Stokes’ shifts. In addition, the fluorescence signal of long-lived fluorophores can be gated to eliminate the emission from short-lifetime fluorophores and autofluorescence from cells and biomolecules to further improve sensitivity.