庆大霉素 硫酸酯 来源于紫红小单孢菌

• 产品号: 48760
• CAS号: 1405-41-0
• 分子式: C60H125N15O25S
• 分子量: 1488.785

产品别名

• 标题: Gentamicin sulfate from Micromonospora purpurea
• IUPAC标准名: (2R,3R,4R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; (2R,3R,4R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[(1R)-1-(methylamino)ethyl]oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; (2R,3R,4R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; sulfuric acid
• IUPAC传统名: (2R,3R,4R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; (2R,3R,4R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[(1R)-1-(methylamino)ethyl]oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; (2R,3R,4R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; sulfuric acid

产品登记号

• MDL号: MFCD00270181
• EC号: 215-778-9
• CAS号: 1405-41-0

产品性质

• 杂质: ≤10% water
• 线性分子式: C19-21H39-43N5O7 · 2.5H2SO4
• Mol. Weight: Mr 694-723
• 比旋光度: [α]20/D +110±8°, c = 1% in H2O
• pH值: 4.0-5.5 (0.1 g/mL in H2O)
• 溶解度: H2O: soluble0.1 g/mL, clear, very faintly yellow
• GHS警示词: Danger
• GHS危险声明: H317-H334
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P261-P280-P342 + P311
• 危险公开号: 42/43
• RTECS编号: LY2625000
• 安全公开号: 22-36/37-45
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Application
Used as a selection agent (gentamicin-resistance gene) in molecular biology applications.
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis by binding to L6 protein of 50S ribosomal subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.
Unit Definition
1 U corresponds to 1 μg of the USP gentamicin sulfate reference standard

详细说明 (简体中文)

Application
Used as a selection agent (gentamicin-resistance gene) in molecular biology applications.
Biochem/physiol Actions
作用方式：通过结合到 50S 核糖体亚基的 L6 蛋白上抑制蛋白质的合成。 抗菌谱：革兰氏阴性菌、革兰氏阳性菌和支原体。
Unit Definition
1U 对应于 1μg USP 级硫酸庆大霉素标准品