1,8-Dihydroxy-3-methylanthraquinone

• 产品号: 229075
• CAS号: 481-74-3
• 分子式: C15H10O4
• 分子量: 254.2375
• 纯 度: 98%

产品别名

• 标题: 1,8-Dihydroxy-3-methylanthraquinone
• IUPAC标准名: 1,8-dihydroxy-3-methyl-9,10-dihydroanthracene-9,10-dione
• IUPAC传统名: turkey rhubarb
• 别名: Chrysophanic acid

产品登记号

• EC号: 207-572-2
• MDL号: MFCD00001208
• CAS号: 481-74-3
• PubChem SID: 24853726
• Beilstein号: 1252300

产品性质

• Empirical Formula (Hill Notation): C15H10O4
• 纯度: 98%
• 相关基因信息: human ... ELA2(1991)
• GHS警示词: Warning
• GHS危险声明: H315-H319
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P305 + P351 + P338
• 危险公开号: 36/38
• RTECS编号: CB6725000
• 安全公开号: 26
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
1 g in glass bottle
50 mg in glass bottle
Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.

详细说明 (简体中文)

包装
1 g in glass bottle
50 mg in glass bottle
Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.