Ilmofosine

• 产品号: I2409
• CAS号: 83519-04-4
• 分子式: C26H56NO5PS
• 分子量: 525.765301

产品别名

• 标题: Ilmofosine
• IUPAC标准名: 3-(hexadecylsulfanyl)-2-(methoxymethyl)propyl 2-(trimethylazaniumyl)ethyl phosphate
• IUPAC传统名: ilmofosine
• 别名: BM 41.440; 1-Hexadecylmercapto-2-methoxymethyl-3-propyl phosphoric acid monocholine ester

产品登记号

• CAS号: 83519-04-4
• MDL号: MFCD00869023
• PubChem SID: 24724510

产品性质

• Empirical Formula (Hill Notation): C26H56NO5PS
• 外观: semisolid (waxy)
• 溶解度: H2O: soluble10 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 22
• RTECS编号: JH4758000
• 保存温度: -20°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
Air-sensitive, sealed under nitrogen
Biochem/physiol Actions
Protein Kinase C (PKC) inhibitor; an ether lipid derivative of lysophosphatidylcholine has antineoplastic activity in vitro and in vivo. IC50 = 560 nM. Competitive at the regulatory site of PKC. Ilmofosine is active against a variety of explanted human non-small cell lung, breast, colorectal, ovarian, renal cell cancer, and melanoma tumors in vitro at concentrations of 1-30 μg/mL.

详细说明 (简体中文)

包装
Air-sensitive, sealed under nitrogen
Biochem/physiol Actions
Protein Kinase C (PKC) inhibitor; an ether lipid derivative of lysophosphatidylcholine has antineoplastic activity in vitro and in vivo. IC50 = 560 nM. Competitive at the regulatory site of PKC. Ilmofosine is active against a variety of explanted human non-small cell lung, breast, colorectal, ovarian, renal cell cancer, and melanoma tumors in vitro at concentrations of 1-30 μg/mL.