Chromeceptin

• 产品号: C0868
• CAS号: 331859-86-0
• 分子式: C19H16F3N3O
• 分子量: 359.3450496
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Chromeceptin
• IUPAC标准名: 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile
• IUPAC传统名: 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile
• 别名: 94G6; 2-Amino-3-cyano-7-dimethylamino-4-(3-trifluoromethylphenyl)-4H-chromene

产品登记号

• CAS号: 331859-86-0
• MDL号: MFCD00815850
• PubChem SID: 24724431

产品性质

• Empirical Formula (Hill Notation): C19H16F3N3O
• 纯度: ≥98% (HPLC)
• 外观: yellow to brown solid
• 溶解度: H2O: <2 mg/mL
• 溶解度: DMSO: >20 mg/mL
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals.

详细说明 (简体中文)

Biochem/physiol Actions
Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals.