A-85783

• 产品号: A1471
• CAS号: 161395-33-1
• 分子式: C29H23FN4O2S
• 分子量: 510.5819232

产品别名

• 标题: A-85783
• IUPAC标准名: 6-(4-fluorophenyl)-N,N-dimethyl-3-[(3R)-3-(pyridin-3-yl)-1H,3H-pyrrolo[1,2-c][1,3]thiazole-7-carbonyl]-1H-indole-1-carboxamide
• IUPAC传统名: 6-(4-fluorophenyl)-N,N-dimethyl-3-[(3R)-3-(pyridin-3-yl)-1H,3H-pyrrolo[1,2-c][1,3]thiazole-7-carbonyl]indole-1-carboxamide
• 别名: (R)-6-(4-Fluorophenyl)-N,N-dimethyl-3-[3-(3-pyridinyl)-1H,3H-pyrrolo[1,2-c]thiazol-7-yl]carbonyl-1H-indole-1-carboxamide

产品登记号

• CAS号: 161395-33-1
• MDL号: MFCD00935061

产品性质

• Empirical Formula (Hill Notation): C29H23FN4O2S
• 熔点: 185.3-186.5 °C(lit.)
• 溶解度: DMSO: soluble13 mg/mL
• 溶解度: H2O: insoluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Potent and selective platelet-activating factor (PAF) receptor antagonist.
General description
Shown to be effective both in vivo and in vitro. A-85783 is neutral and lipophilic and has been shown to competitively and reversibly inhibit [3H]PAF binding to rabbit platelet membranes as well as block PAF-induced serotonin release from rabbit platelets.
Legal Information
Sold under license from Abbott Laboratories.

详细说明 (简体中文)

Biochem/physiol Actions
Potent and selective platelet-activating factor (PAF) receptor antagonist.
General description
Shown to be effective both in vivo and in vitro. A-85783 is neutral and lipophilic and has been shown to competitively and reversibly inhibit [3H]PAF binding to rabbit platelet membranes as well as block PAF-induced serotonin release from rabbit platelets.
Legal Information
Sold under license from Abbott Laboratories.