JC-1

• 产品号: T4069
• CAS号: 3520-43-2
• 分子式: C25H27Cl4IN4
• 分子量: 652.22515

产品别名

• 标题: JC-1
• IUPAC标准名: 5,6-dichloro-2-{3-[(2E)-5,6-dichloro-1,3-diethyl-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]prop-1-en-1-yl}-1,3-diethyl-1H-1,3-benzodiazol-3-ium iodide
• IUPAC传统名: 5,6-dichloro-2-{3-[(2E)-5,6-dichloro-1,3-diethyl-1,3-benzodiazol-2-ylidene]prop-1-en-1-yl}-1,3-diethyl-1,3-benzodiazol-1-ium iodide
• 别名: 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolocarbocyanine iodide; CBIC2(3); 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide

产品登记号

• MDL号: MFCD00188475
• PubChem SID: 24900193
• CAS号: 3520-43-2

产品性质

• Empirical Formula (Hill Notation): C25H27Cl4IN4
• 外观: solid
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent (λex 520 nm) monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent (λem 596 nm ) "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.

详细说明 (简体中文)

Application
A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent (λex 520 nm) monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent (λem 596 nm ) "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.