Cefmetazole sodium salt

• 产品号: C6048
• CAS号: 56796-39-5
• 分子式: C15H16N7NaO5S3
• 分子量: 493.51621

产品别名

• 标题: Cefmetazole sodium salt
• IUPAC标准名: sodium (6R,7S)-7-{2-[(cyanomethyl)sulfanyl]acetamido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• IUPAC传统名: sodium cefmetazole(1-)

产品登记号

• CAS号: 56796-39-5
• PubChem SID: 24278328
• MDL号: MFCD00214260

产品性质

• 线性分子式: C15H16N7O5S3Na
• 有效期: (limited shelf life, expiry date on the label)
• GHS警示词: Danger
• GHS危险声明: H315-H317-H319-H334-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• GHS警示性声明: P261-P280-P305 + P351 + P338-P342 + P311
• 危险公开号: 36/37/38-42/43
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Application
Cefmetazole is used to study the effect of expression, binding, and inhibition of penicillin-binding proteins (PDPs) other than PBP2 on bacterial cell wall mucopeptide synthesis. Cefmetazole is used to study protein mediated transport of antibiotics .
Cefmetazole is used to study the effect of expression, binding, and inhibition of penicillin-binding proteins (PDPs) other than PBP2 on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cefmetazole disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cefmetazole mimics the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.

详细说明 (简体中文)

Application
Cefmetazole is used to study the effect of expression, binding, and inhibition of penicillin-binding proteins (PDPs) other than PBP2 on bacterial cell wall mucopeptide synthesis. Cefmetazole is used to study protein mediated transport of antibiotics .
Cefmetazole is used to study the effect of expression, binding, and inhibition of penicillin-binding proteins (PDPs) other than PBP2 on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cefmetazole disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cefmetazole mimics the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.