Fostriecin sodium salt from Streptomyces pulveraceus

• 产品号: F4425
• CAS号: 87860-39-7
• 分子式: C19H26NaO9P
• 分子量: 452.367871
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Fostriecin sodium salt from Streptomyces pulveraceus
• IUPAC标准名: sodium (6R)-6-[(3R,4R,6R)-4-(hydrogen phosphonatooxy)-3,6,13-trihydroxy-3-methyltrideca-1,7,9,11-tetraen-1-yl]-5,6-dihydro-2H-pyran-2-one
• IUPAC传统名: sodium (6R)-6-[(3R,4R,6R)-4-(hydrogen phosphonatooxy)-3,6,13-trihydroxy-3-methyltrideca-1,7,9,11-tetraen-1-yl]-5,6-dihydropyran-2-one

产品登记号

• PubChem SID: 24894863
• CAS号: 87860-39-7
• MDL号: MFCD09971059

产品性质

• Empirical Formula (Hill Notation): C19H26NaO9P
• 纯度: ≥98% (HPLC)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: UQ0600000
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
Packaged under argon.
Biochem/physiol Actions
Fostriecin was discovered as an anti-tumor antibiotic isolated from the fermentation beer of Streptomyces pulveraceus (subspecies fostreus). Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo. The antitumor activity of fostriecin originates from its ability to interfere with the reversible phosphorylation of proteins that are critical for progression through the cell cycle.

详细说明 (简体中文)

包装
Packaged under argon.
Biochem/physiol Actions
Fostriecin was discovered as an anti-tumor antibiotic isolated from the fermentation beer of Streptomyces pulveraceus (subspecies fostreus). Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo. The antitumor activity of fostriecin originates from its ability to interfere with the reversible phosphorylation of proteins that are critical for progression through the cell cycle.