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Amifostine

产品号 A5922 公司名称 Sigma Aldrich
CAS号 20537-88-6 公司网站 http://www.sigmaaldrich.com
分子式 C5H15N2O3PS 电 话 1-800-521-8956
分子量 214.222961 传 真
纯 度 ≥97% (TLC) 电子邮件
保 存 Chembase数据库ID: 1014

产品价格信息

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产品别名

标题
Amifostine
IUPAC标准名
({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid
IUPAC传统名
amifostine
别名
2-(3-Aminopropyl)aminoethyl phosphorothioate
WR2721

产品登记号

PubChem SID 24278231
MDL号 MFCD00233058
CAS号 20537-88-6

产品性质

Empirical Formula (Hill Notation) C5H15N2O3PS
纯度 ≥97% (TLC)
外观 powder
GHS危险品标识 GHS07
GHS警示词 Warning
GHS危险声明 H302
欧盟危险性物质标志 有害性(Harmful) 有害性(Harmful) (Xn)
MSDS下载 下载链接
个人保护装置 dust mask type N95 (US), Eyeshields, Gloves
危险公开号 22
RTECS编号 TE6491000
安全公开号 26-36
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Application
Amifostine may provide renal protection during PRRT using somatostatin analogs by mitigating radiation damage and reducing the absorbed kidney radiation dose. Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible.
Biochem/physiol Actions
Radioprotective agent. Selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. Selectivity is due to preferential uptake by normal tissues and subsequent metabolic activation to 2-(3-aminopropyl)aminoethanethiol.
详细说明 (简体中文)
Application
Amifostine may provide renal protection during PRRT using somatostatin analogs by mitigating radiation damage and reducing the absorbed kidney radiation dose. Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible.
Biochem/physiol Actions
Radioprotective agent. Selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. Selectivity is due to preferential uptake by normal tissues and subsequent metabolic activation to 2-(3-aminopropyl)aminoethanethiol.

参考文献