秋水仙素

• 产品号: C9754
• CAS号: 64-86-8
• 分子式: C22H25NO6
• 分子量: 399.437
• 纯 度: ≥95% (HPLC)

产品别名

• 标题: Colchicine
• IUPAC标准名: N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0^2,^7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
• IUPAC传统名: colchicine

产品登记号

• MDL号: MFCD00078484
• Beilstein号: 2228813
• PubChem SID: 24278348
• CAS号: 64-86-8
• EC号: 200-598-5

产品性质

• Empirical Formula (Hill Notation): C22H25NO6
• 纯度: ≥95% (HPLC)
• 相关基因信息: human ... ABCB1(5243), CYP3A4(1576)mouse ... Abcb1a(18671), Abcb1b(18669)
• 外观: white to yellow powder
• 熔点: 150-160 °C (dec.)(lit.)
• 溶解度: ethanol: soluble50 mg/mL
• GHS警示词: Danger
• GHS危险声明: H300 + H330-H318-H340
• 欧盟危险性物质标志: 剧毒(Highly toxic) (T+)
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P201-P260-P264-P280-P284-P301 + P310
• RID/ADR: UN 1544 6.1/PG 1
• 危险公开号: 46-28
• RTECS编号: GH0700000
• 安全公开号: 53-45
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 1544
• 联合国危险货物包装类别(PG): 1
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
1, 5 g in poly bottle
100, 500 mg in poly bottle
Biochem/physiol Actions
Antimitotic agent that disrupts microtubules by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

详细说明 (简体中文)

包装
1, 5 g in poly bottle
100, 500 mg in poly bottle
Biochem/physiol Actions
Antimitotic agent that disrupts microtubules by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.