P 物质 乙酸盐 水合物

• 产品号: S6883
• CAS号: 137348-11-9(freebase)
• 分子式: C65H104N18O16S
• 分子量: 1425.69726
• 纯 度: ≥95% (HPLC)

产品别名

• 标题: Substance P acetate salt hydrate
• IUPAC标准名: (2S)-2-{[(2S)-1-[(2S)-6-amino-2-{[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}hexanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-3-carbamoyl-1-{[(1S)-1-({1-[({[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl}carbamoyl)-2-phenylethyl]carbamoyl}propyl]pentanediamide acetic acid hydrate
• IUPAC传统名: (2S)-2-{[(2S)-1-[(2S)-6-amino-2-{[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}hexanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-3-carbamoyl-1-{[(1S)-1-({1-[({[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl}carbamoyl)-2-phenylethyl]carbamoyl}propyl]pentanediamide acetic acid hydrate

产品登记号

• CAS号: 137348-11-9(freebase)
• PubChem SID: 24899725
• Beilstein号: 5153552

产品性质

• Empirical Formula (Hill Notation): C63H98N18O13S · xC2H4O2 · yH2O
• Mol. Weight: mol wt 1348 Da by calculation (Average Mass)
• 纯度: ≥95% (HPLC)
• 相关基因信息: human ... TAC1(6863)
• 外观: white powder
• 溶解度: H2O: soluble1 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Biochem/physiol Actions
NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.

详细说明 (简体中文)

Amino Acid Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Biochem/physiol Actions
NK-1 激动剂；强效血管扩张剂和抗高血压剂；诱导唾液分泌；增加毛细血管通透性；诱导肥大细胞脱颗粒；感觉（疼痛）传入中的假定神经递质。