2D 3D 下载放大

GF 109203X
产品号	G2911	公司名称	Sigma Aldrich
CAS号	133052-90-1	公司网站	http://www.sigmaaldrich.com
分子式	C25H24N4O2	电话	1-800-521-8956
分子量	412.48366	传真
纯度	≥90% (HPLC)	电子邮件
保存		Chembase数据库ID: 3426

产品价格信息

请登录

产品别名

标题

GF 109203X

IUPAC标准名

3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

IUPAC传统名

bisindolylmaleimide

别名

3-(N-[Dimethylamino]propyl-3-indolyl)-4-(3-indolyl)maleimide

3-[1-[3-(Dimethylamino)propyl]1H-indol-3-yl]-4-(1Hindol-3-yl)1H-pyrrole-2,5dione

Bisindolylmaleimide I

产品登记号

MDL号	MFCD00236428
CAS号	133052-90-1

产品性质

生物来源	synthetic
Empirical Formula (Hill Notation)	C25H24N4O2
纯度	≥90% (HPLC)
溶解度	DMSO: soluble (~1 mg/ml)
欧盟危险性物质标志	有害性(Harmful) (Xn)
MSDS下载	下载链接
危险公开号	40
安全公开号	36/37
保存温度	2-8°C
德国WGK号	3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
A potent and selective competitive inhibitor of protein kinase C (PKC) and of glycogen synthase kinase-3 (GSK-3). In certain cells, inhibition of PKC leads to an increase in autophagy. For PKC inhibition, typically used at a concentration of 0.1-10 μM.
A potent and selective competitive inhibitor of protein kinase C (PKC) and of glycogen synthase kinase-3 (GSK-3). Inhibits parathyroid hormone-induced Ca2+ resorption from isolated bone tissue, Staurosporine, another protein kinase inhibitor, actually enhanced Ca2+ resorption elicited by a number of agents, but GF109203X counteracted that enhancement.1
Quantity
For PKC inhibition, typically used at a concentration of 0.1-10 μM.

详细说明 (简体中文)

Biochem/physiol Actions
A potent and selective competitive inhibitor of protein kinase C (PKC) and of glycogen synthase kinase-3 (GSK-3). In certain cells, inhibition of PKC leads to an increase in autophagy. For PKC inhibition, typically used at a concentration of 0.1-10 μM.
A potent and selective competitive inhibitor of protein kinase C (PKC) and of glycogen synthase kinase-3 (GSK-3). Inhibits parathyroid hormone-induced Ca2+ resorption from isolated bone tissue, Staurosporine, another protein kinase inhibitor, actually enhanced Ca2+ resorption elicited by a number of agents, but GF109203X counteracted that enhancement.1
Quantity
For PKC inhibition, typically used at a concentration of 0.1-10 μM.