Acetyl-Amyloid β-Protein Fragment 15-20 Amide

• 产品号: A6933
• CAS号: 189064-06-0
• 分子式: C42H63N9O8
• 分子量: 822.00512
• 纯 度: ≥97% (HPLC)

产品别名

• 标题: Acetyl-Amyloid β-Protein Fragment 15-20 Amide
• IUPAC标准名: (2S)-N-[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-methylbutyl]carbamoyl}pentyl]-2-acetamidopentanediamide
• IUPAC传统名: (2S)-N-[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-methylbutyl]carbamoyl}pentyl]-2-acetamidopentanediamide
• 别名: Ac-QKLVFF-NH2; amyloid blocker

产品登记号

• CAS号: 189064-06-0
• MDL号: MFCD17215285

产品性质

• Empirical Formula (Hill Notation): C42H63N9O8
• 纯度: ≥97% (HPLC)
• 相关基因信息: human ... APP(351)
• 外观: white powder
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2
Biochem/physiol Actions
Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.

详细说明 (简体中文)

Amino Acid Sequence
Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2
Biochem/physiol Actions
Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.