5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester

• 产品号: A3282
• CAS号: 60117-35-3
• 分子式: C11H7N5O6
• 分子量: 305.20318
• 纯 度: ≥95%

产品别名

• 标题: 5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester
• IUPAC标准名: 2,5-dioxopyrrolidin-1-yl 5-azido-2-nitrobenzoate
• IUPAC传统名: 2,5-dioxopyrrolidin-1-yl 5-azido-2-nitrobenzoate
• 别名: N-Succinimidyl 5-azido-2-nitrobenzoate; N-(5-Azido-2-nitrobenzoyloxy)succinimide

产品登记号

• CAS号: 60117-35-3
• Beilstein号: 1555224
• MDL号: MFCD00054962

产品性质

• Empirical Formula (Hill Notation): C11H7N5O6
• 纯度: ≥95%
• 外观: yellow powder
• 溶解度: ethyl acetate: soluble25 mg/mL
• 溶解度: DMF: soluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Photoactive, heterobifunctional cross-linking reagent. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. Second bonding occurs during UV irradiation (250-350 nm) via reactive nitrene. The latter bonding is rapid and non-specific.
Caution
Reducing agents such as thiols may reduce the azide to amine and should be avoided. Initial manipulations and coupling should be performed under reduced light.
Other Notes
Note that the nitro substituent provides an absorption band at a longer wavelength compared to simple aryl azide.

详细说明 (简体中文)

Application
Photoactive, heterobifunctional cross-linking reagent. Typically, initial reaction couples via ester to primary amine by amide bond formation in the pH range 6.5-8.5. Second bonding occurs during UV irradiation (250-350 nm) via reactive nitrene. The latter bonding is rapid and non-specific.
Caution
Reducing agents such as thiols may reduce the azide to amine and should be avoided. Initial manipulations and coupling should be performed under reduced light.
Other Notes
Note that the nitro substituent provides an absorption band at a longer wavelength compared to simple aryl azide.