Oxolinic acid

• 产品号: O0877
• CAS号: 14698-29-4
• 分子式: C13H11NO5
• 分子量: 261.23014

产品别名

• 标题: Oxolinic acid
• IUPAC标准名: 5-ethyl-8-oxo-2H,5H,8H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
• IUPAC传统名: ossian
• 别名: 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid

产品登记号

• PubChem SID: 24278604
• Beilstein号: 620635
• MDL号: MFCD00056775
• CAS号: 14698-29-4
• EC号: 238-750-8

产品性质

• Empirical Formula (Hill Notation): C13H11NO5
• 适用性: suitable for 1694 per US EPA
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• RTECS编号: JI5075000
• 安全公开号: 22-24/25
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Oxolinic acid is a quinolone antibiotic used for studies on DNA winding and coiling and for studies on dopaminergic neurotransmission processes. It is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia coli and Salmonella enterica. It is added to culture medium for the isolation of Gardnerella vaginalis1.
Biochem/physiol Actions
Oxolinic acid is a DNA-gyrase (topoisomerase II) inhibitor used for studies on DNA winding and coiling. Acts as a dopamine reuptake inhibitor for studies on dopaminergic neurotransmission processes.

详细说明 (简体中文)

Application
Oxolinic acid is a quinolone antibiotic used for studies on DNA winding and coiling and for studies on dopaminergic neurotransmission processes. It is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia coli and Salmonella enterica. It is added to culture medium for the isolation of Gardnerella vaginalis1.
Biochem/physiol Actions
Oxolinic acid is a DNA-gyrase (topoisomerase II) inhibitor used for studies on DNA winding and coiling. Acts as a dopamine reuptake inhibitor for studies on dopaminergic neurotransmission processes.