Erythromycin ethyl succinate

• 产品号: E8755
• CAS号: 1264-62-6
• 分子式: C43H75NO16
• 分子量: 862.0527

产品别名

• 标题: Erythromycin ethyl succinate
• IUPAC标准名: 4-(dimethylamino)-2-({14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradecan-6-yl}oxy)-6-methyloxan-3-yl 1-ethyl butanedioate
• IUPAC传统名: erythromycin ethylsuccinate

产品登记号

• EC号: 215-033-8
• PubChem SID: 24894684
• MDL号: MFCD00084692
• CAS号: 1264-62-6

产品性质

• GHS警示性声明: P261-P280-P342 + P311
• 危险公开号: 42/43
• RTECS编号: WM9800000
• 安全公开号: 36
• 德国WGK号: 2
• GHS警示词: Danger
• GHS危险声明: H317-H334
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Empirical Formula (Hill Notation): C43H75NO16

产品详细信息

详细说明 (English)

Application
Erythromycin ethyl succinate is used to study erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae1. It has been used to study down-regulation of motilin receptors on rabbit colon myocytes2 and lethal mutations in outer membrane genes omsA and firA in Salmonella typhimurium3.
Biochem/physiol Actions
Erythromycin ethyl succinate inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).
Erythromycin inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site) by binding to the 50s subunit of the bacterial 70s rRNA complex.

详细说明 (简体中文)

Application
Erythromycin ethyl succinate is used to study erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae1. It has been used to study down-regulation of motilin receptors on rabbit colon myocytes2 and lethal mutations in outer membrane genes omsA and firA in Salmonella typhimurium3.
Biochem/physiol Actions
Erythromycin ethyl succinate inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).
Erythromycin inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site) by binding to the 50s subunit of the bacterial 70s rRNA complex.