L-Aspartic acid β-hydroxamate

• 产品号: A6508
• CAS号: 1955-68-6
• 分子式: C4H8N2O4
• 分子量: 148.11732

产品别名

• 标题: L-Aspartic acid β-hydroxamate
• IUPAC标准名: (2S)-2-amino-3-(hydroxycarbamoyl)propanoic acid
• IUPAC传统名: L-aspartic acid β-hydroxamate
• 别名: HDX; AAH; LAH

产品登记号

• PubChem SID: 24891095
• CAS号: 1955-68-6
• MDL号: MFCD00050389

产品性质

• Empirical Formula (Hill Notation): C4H8N2O4
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
L-Aspartic acid β-hydroxamate (AAH) is used as an inhibitor for the studying the specificity and kinetics of serine racemases.1 AAH has demonstrated antioxidant activity and competitive inhibition against angiotensin converting enzyme (ACE).2 L-Aspartate-β-hydroxamate was effective in promoting the editing activity of asparaginyl-tRNA synthetase (AsnRS) from Brugia malayi and Staphylococcus epidermidis.3 AAH was found to be cytotoxic against L5178Y leukemia cells but with lower tolerance in DBA/2 mice than the D-isomer.4
L-Aspartic acid β-hydroxamate (AAH) is used as an inhibitor for the studying the specificity and kinetics of serine racemase(s) and angiotensin converting enzyme(s) (ACE).

详细说明 (简体中文)

Biochem/physiol Actions
L-Aspartic acid β-hydroxamate (AAH) is used as an inhibitor for the studying the specificity and kinetics of serine racemases.1 AAH has demonstrated antioxidant activity and competitive inhibition against angiotensin converting enzyme (ACE).2 L-Aspartate-β-hydroxamate was effective in promoting the editing activity of asparaginyl-tRNA synthetase (AsnRS) from Brugia malayi and Staphylococcus epidermidis.3 AAH was found to be cytotoxic against L5178Y leukemia cells but with lower tolerance in DBA/2 mice than the D-isomer.4