Chromomycin A3 from Streptomyces griseus

• 产品号: C2659
• CAS号: 7059-24-7
• 分子式: C57H82O26
• 分子量: 1183.24538
• 纯 度: ≥95% (HPLC)

产品别名

• 标题: Chromomycin A3 from Streptomyces griseus
• IUPAC标准名: (2S,3S,4S)-6-{[(2S,3S,4S)-6-{[(2R,3R,4R)-6-{[(2S,3S)-6-{[(4S,5R,6S)-5-(acetyloxy)-4-{[(4S,5S,6S)-4-hydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-3-[(1R,3S,4S)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-8,9-dihydroxy-7-methyl-1-oxo-1,2,3,4-tetrahydroanthracen-2-yl]oxy}-3-hydroxy-2-methyloxan-4-yl]oxy}-3-hydroxy-2-methyloxan-4-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl acetate
• IUPAC传统名: (2S,3S,4S)-6-{[(2S,3S,4S)-6-{[(2R,3R,4R)-6-{[(2S,3S)-6-{[(4S,5R,6S)-5-(acetyloxy)-4-{[(4S,5S,6S)-4-hydroxy-5-methoxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-3-[(1R,3S,4S)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-8,9-dihydroxy-7-methyl-1-oxo-3,4-dihydro-2H-anthracen-2-yl]oxy}-3-hydroxy-2-methyloxan-4-yl]oxy}-3-hydroxy-2-methyloxan-4-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl acetate

产品登记号

• CAS号: 7059-24-7
• PubChem SID: 24892514
• MDL号: MFCD00043151
• EC号: 230-348-0

产品性质

• Empirical Formula (Hill Notation): C57H82O26
• 纯度: ≥95% (HPLC)
• GHS警示词: Danger
• GHS危险声明: H300-H360
• 欧盟危险性物质标志: 剧毒(Highly toxic) (T+)
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P201-P264-P301 + P310-P308 + P313
• RID/ADR: UN 3462 6.1/PG 1
• 危险公开号: 61-28
• RTECS编号: GB7875000
• 安全公开号: 53-28-36/37/39-45
• 保存温度: -20°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 3462
• 联合国危险货物包装类别(PG): 1
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
An antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities. Serves as a fluorescent DNA stain. Useful for the detection of protamine deficiency in sperm chromatin. The compound blocks macromolecule synthesis by a specific, reversible interaction with DNA in the presence of bivalent metal ions. Binding to DNA minor groove mediates an efficient competitive inhibition of DNA gyrase and significantly affects topoisomerase II activity.

详细说明 (简体中文)

Biochem/physiol Actions
An antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities. Serves as a fluorescent DNA stain. Useful for the detection of protamine deficiency in sperm chromatin. The compound blocks macromolecule synthesis by a specific, reversible interaction with DNA in the presence of bivalent metal ions. Binding to DNA minor groove mediates an efficient competitive inhibition of DNA gyrase and significantly affects topoisomerase II activity.