芦丁 水合物

• 产品号: R5143
• CAS号: 207671-50-9
• 分子式: C27H36O19
• 分子量: 664.56334
• 纯 度: ≥94% (HPLC)

产品别名

• 标题: Rutin hydrate
• IUPAC标准名: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one trihydrate
• IUPAC传统名: troxerutin trihydrate
• 别名: Quercetin-3-rutinoside hydrate; Vitamin P 水合物; Vitamin P hydrate; Quercetin-3-rutinoside 水合物

产品登记号

• MDL号: MFCD00149490
• Beilstein号: 75455
• EC号: 205-814-1
• CAS号: 207671-50-9
• PubChem SID: 24899379

产品性质

• Empirical Formula (Hill Notation): C27H30O16 · xH2O
• 纯度: ≥94% (HPLC)
• 外观: yellow to green powder
• 熔点: 195 °C (dec.)(lit.)
• 溶解度: pyridine: soluble50 mg/mL
• 溶解度: DMSO: soluble
• 溶解度: aqueous base: soluble
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodimethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.
Protocols & Applications
Ginkgo (Ginkgo biloba) Plant Profile: bioactives, mechanism of action, references

详细说明 (简体中文)

Biochem/physiol Actions
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodimethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.
Protocols & Applications
Ginkgo (Ginkgo biloba) Plant Profile: bioactives, mechanism of action, references