氯霉素

• 产品号: C0378
• CAS号: 56-75-7
• 分子式: C11H12Cl2N2O5
• 分子量: 323.12938
• 纯 度: ≥98% (TLC)

产品别名

• 标题: Chloramphenicol
• IUPAC标准名: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• IUPAC传统名: chloromycetin
• 别名: D(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide; D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide; D-(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide; Chloromycetin

产品登记号

• MDL号: MFCD00078159
• Beilstein号: 2225532
• PubChem SID: 24892250
• CAS号: 56-75-7
• EC号: 200-287-4

产品性质

• 线性分子式: Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
• 纯度: ≥98% (TLC)
• 产品质量级别: PREMIUM
• 相关基因信息: human ... CYP1A2(1544)
• 熔点: 148-150 °C(lit.)
• GHS警示词: Danger
• GHS危险声明: H350
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P201-P308 + P313
• 危险公开号: 45
• RTECS编号: AB6825000
• 安全公开号: 53-45
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
Packaging
1 kg in poly bottle
5, 25, 100, 500 g in poly bottle
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

详细说明 (简体中文)

Application
Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
包装
1 kg in poly bottle
5, 25, 100, 500 g in poly bottle
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information