Fluvastatin sodium hydrate

• 产品号: SML0038
• 分子式: C24H27FNNaO5
• 分子量: 451.4630532
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Fluvastatin sodium hydrate
• IUPAC标准名: sodium (3R,5S)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate hydrate
• IUPAC传统名: sodium (3R,5S)-7-[3-(4-fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxyhept-6-enoate hydrate
• 别名: (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt hydrate

产品登记号

• MDL号: MFCD20488050

产品性质

• Empirical Formula (Hill Notation): C24H25FNO4 ·Na · xH2O
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: H2O: ≥9 mg/mL
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.

详细说明 (简体中文)

Biochem/physiol Actions
Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.