GW788388 Hydrate

• 产品号: SML0116
• 分子式: C25H25N5O3
• 分子量: 443.4977
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: GW788388 Hydrate
• IUPAC标准名: N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}benzamide hydrate
• IUPAC传统名: N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}benzamide hydrate
• 别名: 4-{4-[3-(Pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide hydrate

产品登记号

• MDL号: MFCD20527321

产品性质

• Empirical Formula (Hill Notation): C25H23N5O2 · xH2O
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: ≥8 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301-H400
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273-P301 + P310
• 危险公开号: 25-50/53
• 安全公开号: 60-61
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
GW788388 is a potent selective inhibitor of TGF-beta type I receptor [activin receptor-like kinase 5 (ALK5)]. GW788388 is orally available with a half-life of approximately 4 hours.

详细说明 (简体中文)

Biochem/physiol Actions
GW788388 is a potent selective inhibitor of TGF-beta type I receptor [activin receptor-like kinase 5 (ALK5)]. GW788388 is orally available with a half-life of approximately 4 hours.