Salsalate

• 产品号: SML0070
• CAS号: 552-94-3
• 分子式: C14H10O5
• 分子量: 258.2262
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Salsalate
• IUPAC标准名: 2-(2-hydroxybenzoyloxy)benzoic acid
• IUPAC传统名: salina
• 别名: 2-Hydroxybenzoic acid 2-carboxyphenyl ester; disalicylic acid; salicyloxysalicylic acid; 2-(2-Hydroxybenzoyl)oxybenzoic acid; salicylsalicylic acid

产品登记号

• MDL号: MFCD00020252
• CAS号: 552-94-3
• EC号: 209-027-4

产品性质

• Empirical Formula (Hill Notation): C14H10O5
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: ≥15 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H400
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273
• 危险公开号: 22-50
• 安全公开号: 61
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.

详细说明 (简体中文)

Biochem/physiol Actions
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.