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EMD386088

产品号 SML0139 公司名称 Sigma Aldrich
CAS号 1171123-46-8 公司网站 http://www.sigmaaldrich.com
分子式 C14H16Cl2N2 电 话 1-800-521-8956
分子量 283.19624 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 155051

产品价格信息

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产品别名

标题
EMD386088
IUPAC标准名
5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hydrochloride
IUPAC传统名
5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hydrochloride
别名
5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-Indole hydrochloride
EMD-386088

产品登记号

CAS号 1171123-46-8
MDL号 MFCD09038557

产品性质

Empirical Formula (Hill Notation) C14H15ClN2 · HCl
纯度 ≥98% (HPLC)
外观 yellow powder
溶解度 DMSO: ≥16 mg/mL
MSDS下载 下载链接
保存温度 2-8°C

产品详细信息

详细说明 (English)
Biochem/physiol Actions
EMD-386088 is a potent serotonin 5-HT6-specific agonist. The IC50 for competition of LSD from 5-HT6 expressed in HEK cells is 7.4 nM, and the EC50 for stimulating cAMP production is 1 nM. EMD-386088 is inactive against other HT receptors except 5-HT3 (IC50 = 34 nM).
详细说明 (简体中文)
Biochem/physiol Actions
EMD-386088 is a potent serotonin 5-HT6-specific agonist. The IC50 for competition of LSD from 5-HT6 expressed in HEK cells is 7.4 nM, and the EC50 for stimulating cAMP production is 1 nM. EMD-386088 is inactive against other HT receptors except 5-HT3 (IC50 = 34 nM).

参考文献