OBA-09 hydrate

• 产品号: SML0126
• CAS号: 856095-68-6(anhydrous)
• 分子式: C10H10O6
• 分子量: 226.1828
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: OBA-09 hydrate
• IUPAC标准名: 2-[(2-oxopropanoyl)oxy]benzoic acid hydrate
• IUPAC传统名: 2-[(2-oxopropanoyl)oxy]benzoic acid hydrate
• 别名: O-Pyruvoylsalicylic acid hydrate; 2-(1,2-Dioxopropoxy)benzoic acid hydrate

产品登记号

• CAS号: 856095-68-6(anhydrous)
• MDL号: MFCD20488062

产品性质

• Empirical Formula (Hill Notation): C10H8O5 · xH2O
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: ≥24 mg/mL
• 保存条件: desiccated
• 保存温度: 2-8°C

产品详细信息

详细说明 (English)

Biochem/physiol Actions
OBA-09 is a neuroprotective agent. It is an ester of pyruvate and salicylic acid that acts as a multi-functional agent to protect against ischemic damages to the brain. Administration of 5 mpk OBA-09 following middle cerebral artery occlusion (MCAO) or oxygen-glucose deprivation (OGD) models of ischemic injury in rats prevents lipid peroxidation, ROS production and causes the recovery of NAD and ATP concentrations to near basal levels. The compound leads to reduction of infarct volume and also accelerates the recovery of behavioral and neurological deficits.

详细说明 (简体中文)

Biochem/physiol Actions
OBA-09 is a neuroprotective agent. It is an ester of pyruvate and salicylic acid that acts as a multi-functional agent to protect against ischemic damages to the brain. Administration of 5 mpk OBA-09 following middle cerebral artery occlusion (MCAO) or oxygen-glucose deprivation (OGD) models of ischemic injury in rats prevents lipid peroxidation, ROS production and causes the recovery of NAD and ATP concentrations to near basal levels. The compound leads to reduction of infarct volume and also accelerates the recovery of behavioral and neurological deficits.