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Acenocoumarol

产品号 SML0074 公司名称 Sigma Aldrich
CAS号 152-72-7 公司网站 http://www.sigmaaldrich.com
分子式 C19H15NO6 电 话 1-800-521-8956
分子量 353.3255 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 155045

产品价格信息

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产品别名

标题
Acenocoumarol
IUPAC标准名
4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one
IUPAC传统名
acenocumarolo
别名
(±)-Acenocoumarin
3-(α-Acetonyl-p-nitrobenzyl)-4-hydroxy-coumarin

产品登记号

EC号 205-807-3
CAS号 152-72-7
MDL号 MFCD00137816

产品性质

Empirical Formula (Hill Notation) C19H15NO6
纯度 ≥98% (HPLC)
外观 white to tan powder
溶解度 DMSO, heptane and xylene: ≥17 mg/mL
GHS危险品标识 GHS07
GHS警示词 Warning
GHS危险声明 H302-H315-H319-H335
欧盟危险性物质标志 有害性(Harmful) 有害性(Harmful) (Xn)
MSDS下载 下载链接
GHS警示性声明 P261-P305 + P351 + P338
危险公开号 63-22-36/37/38
RTECS编号 GN4900000
安全公开号 26-36/37
保存温度 -20°C
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Acenocoumarol is a warfarin analog, an anticoagulant that inhibits Vitamin K epoxide reductase. This results in depletion of the reduced form of vitamin K (vitamin KH2), limiting the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S, resulting in decreased prothrombin levels and the amount of thrombin generated.
详细说明 (简体中文)
Biochem/physiol Actions
Acenocoumarol is a warfarin analog, an anticoagulant that inhibits Vitamin K epoxide reductase. This results in depletion of the reduced form of vitamin K (vitamin KH2), limiting the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S, resulting in decreased prothrombin levels and the amount of thrombin generated.

参考文献