L 748337 hydrate

• 产品号: L7045
• 分子式: C26H33N3O6S
• 分子量: 515.62172
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: L 748337 hydrate
• IUPAC标准名: N-({3-[(2S)-3-{[2-(4-benzenesulfonamidophenyl)ethyl]amino}-2-hydroxypropoxy]phenyl}methyl)acetamide hydrate
• IUPAC传统名: N-({3-[(2S)-3-{[2-(4-benzenesulfonamidophenyl)ethyl]amino}-2-hydroxypropoxy]phenyl}methyl)acetamide hydrate
• 别名: N-(3-{3-[2-(4-Benzenesulfonylamino-phenyl)-ethylamino]-(2S)-2-hydroxy-propoxy}-benzyl)-acetamide hydrate; Acetamide, N-[[3-[(2S)-2-hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl] hydrate

产品登记号

• MDL号: MFCD20134197

产品性质

• Empirical Formula (Hill Notation): C26H31N3O5S · xH2O
• 纯度: ≥98% (HPLC)
• 外观: powder
• 比旋光度: [α]/D +4.0 to +8.0°, c = 4 in DMSO
• 溶解度: DMSO: >12 mg/mL
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
L 748337 is a selective, competitive beta 3 adrenergic receptor antagonist, that binds to the receptor with an affinity of 04 nM. The affinities for beta-1 and beta-2 receptors are 154 and 204 nM, respectively. The compound potently inhibits agonist-stimulated lipolysis in adipocytes, as well as agonist induced relaxation of smooth muscle.

详细说明 (简体中文)

Biochem/physiol Actions
L 748337 is a selective, competitive beta 3 adrenergic receptor antagonist, that binds to the receptor with an affinity of 04 nM. The affinities for beta-1 and beta-2 receptors are 154 and 204 nM, respectively. The compound potently inhibits agonist-stimulated lipolysis in adipocytes, as well as agonist induced relaxation of smooth muscle.