DBeQ

• 产品号: SML0031
• 分子式: C22H20N4
• 分子量: 340.421
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: DBeQ
• IUPAC标准名: 2-N,4-N-dibenzylquinazoline-2,4-diamine
• IUPAC传统名: 2-N,4-N-dibenzylquinazoline-2,4-diamine
• 别名: JRF 12; N2,N4-dibenzylquinazoline-2,4-diamine

产品登记号

• MDL号: MFCD03691820

产品性质

• 德国WGK号: 3
• GHS警示词: Warning
• GHS危险声明: H302-H319
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• GHS警示性声明: P305 + P351 + P338
• 危险公开号: 22-36
• 安全公开号: 26
• 保存温度: room temp
• Empirical Formula (Hill Notation): C22H20N4
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: DMSO: ≥20 mg/mL

产品详细信息

详细说明 (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
DBeQ is a potent and specific inhibitor of ATPase p97, an integral component of the ubiquitin-fusion degradation (UFD) pathway. DBeQ inhibits the degradation of ubiquitinated proteins, the endoplasmic reticulum-associated degradation pathway, and autophagosome maturation. The compound also potently inhibits cellular proliferation and induces caspase 3/7 activity and apoptosis.

详细说明 (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
DBeQ is a potent and specific inhibitor of ATPase p97, an integral component of the ubiquitin-fusion degradation (UFD) pathway. DBeQ inhibits the degradation of ubiquitinated proteins, the endoplasmic reticulum-associated degradation pathway, and autophagosome maturation. The compound also potently inhibits cellular proliferation and induces caspase 3/7 activity and apoptosis.