NSC 668036 hydrate

• 产品号: SML0046
• CAS号: 144678-63-7(anhydrous)
• 分子式: C21H38N2O10
• 分子量: 478.53382
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: NSC 668036 hydrate
• IUPAC标准名: (2S)-2-{[(2S)-2-[(2S)-2-{[(2S)-2-{[(tert-butoxy)carbonyl]amino}propanoyl]oxy}-3-methylbutanamido]propanoyl]oxy}-3-methylbutanoic acid hydrate
• IUPAC传统名: (2S)-2-{[(2S)-2-[(2S)-2-{[(2S)-2-[(tert-butoxycarbonyl)amino]propanoyl]oxy}-3-methylbutanamido]propanoyl]oxy}-3-methylbutanoic acid hydrate
• 别名: N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-(2S)-2-hydroxy-3-methylbutanoic acid hydrate; N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-Alanine-(1S)-1-carboxy-2-methylpropyl ester hydrate

产品登记号

• CAS号: 144678-63-7(anhydrous)
• MDL号: MFCD20036264

产品性质

• Empirical Formula (Hill Notation): C21H36N2O9 · xH2O
• 纯度: ≥98% (HPLC)
• 运输包装: wet ice
• 外观: white to tan powder
• 溶解度: H2O: ≥5 mg/mL
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
NSC 668036 binds to the PDZ domain of the Wnt-pathway signaling molecule Disheveled (Dvl), blocking the binding and activation of Dvl by Frizzled. In Xenopus embryos, NSC 668036 inhibited Wnt3A-induced expression of the target gene Siamois and formation of secondary axes.

详细说明 (简体中文)

Biochem/physiol Actions
NSC 668036 binds to the PDZ domain of the Wnt-pathway signaling molecule Disheveled (Dvl), blocking the binding and activation of Dvl by Frizzled. In Xenopus embryos, NSC 668036 inhibited Wnt3A-induced expression of the target gene Siamois and formation of secondary axes.