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Scutellarin hydrate_分子结构_CAS_)
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Scutellarin hydrate

产品号 SML0014 公司名称 Sigma Aldrich
CAS号 公司网站 http://www.sigmaaldrich.com
分子式 C21H18O12 电 话 1-800-521-8956
分子量 462.36042 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 desiccated Chembase数据库ID: 129421

产品价格信息

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产品别名

标题
Scutellarin hydrate
IUPAC标准名
(2S,3S,4S,5R,6S)-6-{[5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
IUPAC传统名
scutellarin
别名
5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid hydrate
Scutellarein-7-O-β-D-glucuronide
7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate
Breviscapin

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产品性质

Empirical Formula (Hill Notation) C21H18O12 · xH2O
纯度 ≥98% (HPLC)
外观 yellow powder
溶解度 DMSO: ≥10 mg/mL
MSDS下载 下载链接
保存条件 desiccated
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.
详细说明 (简体中文)
Biochem/physiol Actions
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

参考文献