Diethylumbelliferyl phosphate

• 产品号: D7692
• CAS号: 897-83-6
• 分子式: C13H15O6P
• 分子量: 298.228361
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Diethylumbelliferyl phosphate
• IUPAC标准名: diethyl 2-oxo-2H-chromen-7-yl phosphate
• IUPAC传统名: diethyl 2-oxochromen-7-yl phosphate
• 别名: DEUP; UBP

产品登记号

• CAS号: 897-83-6
• PubChem SID: 24894155

产品性质

• Empirical Formula (Hill Notation): C14H17O6P
• 纯度: ≥98% (HPLC)
• 外观: colorless to yellow oil
• 溶解度: DMSO: >5 mg/mL
• GHS警示词: Danger
• GHS危险声明: H300
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P264-P301 + P310
• RID/ADR: UN 2811 6.1/PG 2
• 危险公开号: 25
• RTECS编号: GN7350000
• 安全公开号: 45
• 保存温度: -20°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 2
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.

详细说明 (简体中文)

Biochem/physiol Actions
Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.