Repaglinide

• 产品号: R9028
• CAS号: 135062-02-1
• 分子式: C27H36N2O4
• 分子量: 452.58574
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Repaglinide
• IUPAC标准名: 2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid
• IUPAC传统名: repaglinide
• 别名: NovoNorm; (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid; Prandin

产品登记号

• MDL号: MFCD00906179
• CAS号: 135062-02-1
• PubChem SID: 24724596

产品性质

• Empirical Formula (Hill Notation): C27H36N2O4
• 纯度: ≥98% (HPLC)
• 相关基因信息: human ... KCNJ1(3758)
• 外观: white solid
• 熔点: 129-130.2 °C
• 溶解度: DMSO: >20 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: DI0876305
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Repaglinide is a potent short-acting insulin secretagogue that acts by closing ATP-sensitive potassium (KATP) channels in the plasma membrane of the pancreatic beta cell. It represents a new class of insulin secretagogues, structurally unrelated to sulphonylureas, which were developed for the treatment of type 2 diabetes.

详细说明 (简体中文)

Biochem/physiol Actions
Repaglinide is a potent short-acting insulin secretagogue that acts by closing ATP-sensitive potassium (KATP) channels in the plasma membrane of the pancreatic beta cell. It represents a new class of insulin secretagogues, structurally unrelated to sulphonylureas, which were developed for the treatment of type 2 diabetes.