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多拉克汀 合成的_分子结构_CAS_117704-25-3)
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多拉克汀 合成的

产品号 D6696 公司名称 Sigma Aldrich
CAS号 117704-25-3 公司网站 http://www.sigmaaldrich.com
分子式 C50H74O14 电 话 1-800-521-8956
分子量 899.11416 传 真
纯 度 ≥90% 电子邮件
保 存 Chembase数据库ID: 154974

产品价格信息

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产品别名

标题
Doramectin synthetic
IUPAC标准名
(1'R,2S,4'S,5S,6R,12'S,13'S,20'R,21'R,24'S)-6-cyclohexyl-21',24'-dihydroxy-12'-{[(2S,4S,5S,6S)-5-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-5,6-dihydro-3',7',19'-trioxaspiro[pyran-2,6'-tetracyclo[15.6.1.14,8.020,24]pentacosane]-10',14',16',22'-tetraen-2'-one
IUPAC传统名
(1'R,2S,4'S,5S,6R,12'S,13'S,20'R,21'R,24'S)-6-cyclohexyl-21',24'-dihydroxy-12'-{[(2S,4S,5S,6S)-5-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-5,6-dihydro-3',7',19'-trioxaspiro[pyran-2,6'-tetracyclo[15.6.1.14,8.020,24]pentacosane]-10',14',16',22'-tetraen-2'-one
别名
25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin
多拉克汀
Doramectin
25-环己基-5-O-去甲基-25-去(1-甲基丙基)阿维菌素

产品登记号

CAS号 117704-25-3
MDL号 MFCD00894747

产品性质

生物来源 from synthetic
Empirical Formula (Hill Notation) C50H74O14
杂质 ≤5% water (Karl Fischer)
纯度 ≥90%
GHS危险品标识 GHS06
GHS危险品标识 GHS09
GHS警示词 Danger
GHS危险声明 H301-H410
欧盟危险性物质标志 有毒(Toxic) 有毒(Toxic) (T)
欧盟危险性物质标志 环境危害性(Nature polluting) 环境危害性(Nature polluting) (N)
MSDS下载 下载链接
GHS警示性声明 P273-P301 + P310-P501
危险公开号 25-50/53
安全公开号 33-45-60-61
德国WGK号 3

产品详细信息

详细说明 (English)
Application
Doramectin is commonly used in veterinary medicine for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites. It is effective against Haemonchus spp., Ostertagia spp., Trichostrongylus spp., Cooperia spp., Oesophagostomum spp., Dyctiocaulus viviparus, Dermatobia hominis, Boophilus microplus, Psoroptes bovis, as well as other internal and external parasites1,2.
Biochem/physiol Actions
Doramectin is a derivative of ivermectin. It is thought to work like other macrocyclic lactones by opening glutamate-gated chloride channels in the nerve cells, causing paralysis.
详细说明 (简体中文)
Application
Doramectin is commonly used in veterinary medicine for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites. It is effective against Haemonchus spp., Ostertagia spp., Trichostrongylus spp., Cooperia spp., Oesophagostomum spp., Dyctiocaulus viviparus, Dermatobia hominis, Boophilus microplus, Psoroptes bovis, as well as other internal and external parasites1,2.
Biochem/physiol Actions
Doramectin is a derivative of ivermectin. It is thought to work like other macrocyclic lactones by opening glutamate-gated chloride channels in the nerve cells, causing paralysis.

参考文献