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Alpidem

产品号 A1862 公司名称 Sigma Aldrich
CAS号 82626-01-5 公司网站 http://www.sigmaaldrich.com
分子式 C21H23Cl2N3O 电 话 1-800-521-8956
分子量 404.33282 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 154963

产品价格信息

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产品别名

标题
Alpidem
IUPAC标准名
2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]-N,N-dipropylacetamide
IUPAC传统名
alpidem
别名
SL 80.0342-00
6-Chloro-2-(4-chlorophenyl)-N,N-dipropyl-imidazo[1,2-a]pyridine-3-acetamide
6-Chloro-2-(p-chlorophenyl)-N,N-dipropylimidazo(1,2-a)pyridine-3-acetamide
Ananxyl

产品登记号

MDL号 MFCD00866978
CAS号 82626-01-5

产品性质

Empirical Formula (Hill Notation) C21H23Cl2N3O
纯度 ≥98% (HPLC)
外观 white to tan powder
溶解度 DMSO: ≥10 mg/mL
GHS危险品标识 GHS07
GHS警示词 Warning
GHS危险声明 H302
MSDS下载 下载链接
保存温度 2-8°C

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Alpidem is a potent antagonist of peripheral benzodiazepine receptor (PBR) that is located on the outer mitochondrial membrane and interacts with the mitochondrial permeability transition (MPT) pore. Alpidem is an anxiolytic drug from the imidazopyridine family. Alpidem acts selectively on the α3 receptor subtype and to a lesser extent at the α1 subtype (Kd of 0.33nM and 1.67nM respectively), of the benzodiazepine receptor.
详细说明 (简体中文)
Biochem/physiol Actions
Alpidem is a potent antagonist of peripheral benzodiazepine receptor (PBR) that is located on the outer mitochondrial membrane and interacts with the mitochondrial permeability transition (MPT) pore. Alpidem is an anxiolytic drug from the imidazopyridine family. Alpidem acts selectively on the α3 receptor subtype and to a lesser extent at the α1 subtype (Kd of 0.33nM and 1.67nM respectively), of the benzodiazepine receptor.

参考文献