2’-C-Methylcytidine

• 产品号: M4949
• CAS号: 20724-73-6
• 分子式: C10H15N3O5
• 分子量: 257.2432
• 纯 度: ≥95% (HPLC)
• 保 存: desiccated

产品别名

• 标题: 2’-C-Methylcytidine
• IUPAC标准名: 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2-one
• IUPAC传统名: 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one
• 别名: NM107; 2′-C-Methyl Cytidine

产品登记号

• CAS号: 20724-73-6
• MDL号: MFCD02682947

产品性质

• Empirical Formula (Hill Notation): C10H15N3O5
• 纯度: ≥95% (HPLC)
• 外观: white to off-white powder
• 溶解度: H2O: >20 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26
• 保存条件: desiccated
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.

详细说明 (简体中文)

Biochem/physiol Actions
2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.