D12-116 trifluoroacetate salt

• 产品号: D0447
• 分子式: C60H95F3N16O21
• 分子量: 1433.4861096
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: D12-116 trifluoroacetate salt
• IUPAC标准名: (4S)-4-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-4-{[(1S)-1-{[(1S,2S)-1-{[(1S)-4-carbamimidamido-1-{[(1S,2S)-1-[({[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-{[(1S)-3-carbamoyl-1-carboxypropyl]carbamoyl}-2-hydroxyethyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}-2-methylpropyl]carbamoyl}methyl)carbamoyl]-2-methylbutyl]carbamoyl}butyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid; trifluoroacetic acid
• IUPAC传统名: (4S)-4-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-4-{[(1S)-1-{[(1S,2S)-1-{[(1S)-4-carbamimidamido-1-{[(1S,2S)-1-[({[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-{[(1S)-3-carbamoyl-1-carboxypropyl]carbamoyl}-2-hydroxyethyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}-2-methylpropyl]carbamoyl}methyl)carbamoyl]-2-methylbutyl]carbamoyl}butyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid; trifluoroacetic acid
• 别名: L-Tyrosyl-L-a-glutamyl-L-seryl-L-isoleucyl-L-arginyl-L-isoleucylglycyl-L-valyl-L-alanyl-L-prolyl-L-seryl-L-glutamine trifluoroacetate salt; YESIRIGVAPSQ trifluoroacetate salt

产品性质

• Empirical Formula (Hill Notation): C58H94N16O19 · xC2HF3O2
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: H2O: ≥2 mg/mL
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
D12-116 is a specific allosteric modulator of the glycine receptor (GlyR). The peptide D12-116 produces a marked enhancement of GlyR function while not affecting a1b2g2S GABAA receptors.

详细说明 (简体中文)

Biochem/physiol Actions
D12-116 is a specific allosteric modulator of the glycine receptor (GlyR). The peptide D12-116 produces a marked enhancement of GlyR function while not affecting a1b2g2S GABAA receptors.