Nifurtimox

• 产品号: N3415
• CAS号: 23256-30-6
• 分子式: C10H13N3O5S
• 分子量: 287.29232
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Nifurtimox
• IUPAC标准名: 3-methyl-4-[2-(5-nitrofuran-2-yl)diazen-1-yl]-1λ^6-thiane-1,1-dione
• IUPAC传统名: 3-methyl-4-[2-(5-nitrofuran-2-yl)diazen-1-yl]-1λ^6-thiane-1,1-dione
• 别名: BAY 2502; 3-Methyl-4-(5′-nitrofurylidene-amino)-tetrahydro-4H-1,4-thiazine-1,1-dioxide; 4-((5-Nitrofurfurylidene)amino)-3-methylthiomorpholine 1,1-dioxide; Thiomorpholine, 3-methyl-4-((5-nitrofurfurylidene)amino)-,1,1-dioxide; (±)-Nifurtimox; (RS)-3-methyl-N-[(1E)-(5-nitro-2-furyl)methylene]thiomorpholin-4-amine 1,1-dioxide

产品登记号

• CAS号: 23256-30-6
• EC号: 245-531-0

产品性质

• Empirical Formula (Hill Notation): C10H13N3O5S
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: DMSO: ≥13 mg/mL
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Nifurtimox is a nitrofurane derivative used to treat diseases caused by trypanosomes. Nifurtimox was discovered empirically and its mechanism of action is unclear. It is believed that nifurtimox exerts its biological activity through the bioreduction of the nitro-group to a nitro-anion radical which undergoes redox-cycling with molecular oxygen.

详细说明 (简体中文)

Biochem/physiol Actions
Nifurtimox is a nitrofurane derivative used to treat diseases caused by trypanosomes. Nifurtimox was discovered empirically and its mechanism of action is unclear. It is believed that nifurtimox exerts its biological activity through the bioreduction of the nitro-group to a nitro-anion radical which undergoes redox-cycling with molecular oxygen.