Rosiglitazone

• 产品号: R2408
• CAS号: 122320-73-4
• 分子式: C18H19N3O3S
• 分子量: 357.42676
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Rosiglitazone
• IUPAC标准名: 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione
• IUPAC传统名: rosiglitazone
• 别名: rosiglitazone; 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione

产品登记号

• MDL号: MFCD00871760
• CAS号: 122320-73-4

产品性质

• 线性分子式: C18H19N3O3S
• 纯度: ≥98% (HPLC)
• 纯度: ≥98% (HPLC)
• 外观: powder
• 溶解度: DMSO: ≥10 mg/mL
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.

详细说明 (简体中文)

Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.