AG-205

• 产品号: A1487
• 分子式: C22H23ClN6OS
• 分子量: 454.97562
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: AG-205
• IUPAC标准名: 1-[(4aR,9bS)-2,8-dimethyl-1H,2H,3H,4H,4aH,5H,9bH-pyrido[4,3-b]indol-5-yl]-2-{[1-(4-chlorophenyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl}ethan-1-one
• IUPAC传统名: 1-[(4aR,9bS)-2,8-dimethyl-1H,3H,4H,4aH,9bH-pyrido[4,3-b]indol-5-yl]-2-{[1-(4-chlorophenyl)-1,2,3,4-tetrazol-5-yl]sulfanyl}ethanone
• 别名: cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone

产品性质

• Empirical Formula (Hill Notation): C22H23ClN6OS
• 纯度: ≥98% (HPLC)
• 外观: off-white to brown powder
• 溶解度: DMSO: >9 mg/mL (warmed)
• 保存条件: desiccated
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
AG-205 is a Pgrmc1 (progesterone receptor membrane component 1) inhibitor. AG-205 alters the spectroscopic properties of the Pgrmc1-heme complex. AG-205 inhibits cancer cell viability and cancer cell progression. acting preferentially on Pgrmc1-expressing cells.

详细说明 (简体中文)

Biochem/physiol Actions
AG-205 is a Pgrmc1 (progesterone receptor membrane component 1) inhibitor. AG-205 alters the spectroscopic properties of the Pgrmc1-heme complex. AG-205 inhibits cancer cell viability and cancer cell progression. acting preferentially on Pgrmc1-expressing cells.