PD184352

• 产品号: PZ0181
• CAS号: 212631-79-3
• 分子式: C17H14ClF2IN2O2
• 分子量: 478.6595364
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: PD184352
• IUPAC标准名: 2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
• IUPAC传统名: 2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
• 别名: CI-1040; 2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide

产品登记号

• MDL号: MFCD02683961
• CAS号: 212631-79-3

产品性质

• Empirical Formula (Hill Notation): C17H14ClF2IN2O2
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: ≥30 mg/mL
• GHS警示词: Warning
• GHS危险声明: H400
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273
• 危险公开号: 50/53
• 安全公开号: 60-61
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PD184352 (CI-1040) is a highly selective non-competitive inhibitor of MEK (MKK1; MAPK kinase) and the closely related MKK2. It has anti-cancer activity, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell lines.

详细说明 (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PD184352 (CI-1040) is a highly selective non-competitive inhibitor of MEK (MKK1; MAPK kinase) and the closely related MKK2. It has anti-cancer activity, suppresses the ERK pathway, and has been used along with other classes of inhibitors to establish embryonic stem cell lines.