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OPC 31260 hydrochloride_分子结构_CAS_138470-70-9)
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OPC 31260 hydrochloride

产品号 O1266 公司名称 Sigma Aldrich
CAS号 138470-70-9 公司网站 http://www.sigmaaldrich.com
分子式 C27H30ClN3O2 电 话 1-800-521-8956
分子量 463.999 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 154904

产品价格信息

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产品别名

标题
OPC 31260 hydrochloride
IUPAC标准名
N-{4-[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepine-1-carbonyl]phenyl}-2-methylbenzamide hydrochloride
IUPAC传统名
mozavaptan hydrochloride
别名
Mozavaptan hydrochloride
5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine hydrochloride
N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-2-methylbenzamide hydrochloride

产品登记号

CAS号 138470-70-9
MDL号 MFCD11111965

产品性质

Empirical Formula (Hill Notation) C27H29N3O2 · HCl
纯度 ≥98% (HPLC)
外观 white to tan powder
溶解度 DMSO: ≥15 mg/mL
GHS危险品标识 GHS07
GHS警示词 Warning
GHS危险声明 H302
欧盟危险性物质标志 有害性(Harmful) 有害性(Harmful) (Xn)
MSDS下载 下载链接
危险公开号 22
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Caution
air-sensitive, hygroscopic, store with desiccant
Biochem/physiol Actions
OPC 31260 is a vasopressin V2 selective antagonist. Arginine vasopressin (AVP) plays an important part in circulatory and water homeostasis. The V2 receptor subtype is important in water retention, cardiac remodeling in congestive heart failure (CHF), and renal hemodynamic alterations, and is considered a target for polysystic kidney disease. OPC-31260 has been shown to inhibit the development of polycystic kidney disease in several animal models.
详细说明 (简体中文)
Caution
air-sensitive, hygroscopic, store with desiccant
Biochem/physiol Actions
OPC 31260 is a vasopressin V2 selective antagonist. Arginine vasopressin (AVP) plays an important part in circulatory and water homeostasis. The V2 receptor subtype is important in water retention, cardiac remodeling in congestive heart failure (CHF), and renal hemodynamic alterations, and is considered a target for polysystic kidney disease. OPC-31260 has been shown to inhibit the development of polycystic kidney disease in several animal models.

参考文献