Tigecycline hydrate

• 产品号: PZ0021
• CAS号: 1229002-07-6
• 分子式: C29H41N5O9
• 分子量: 603.66394
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Tigecycline hydrate
• IUPAC标准名: (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrate
• IUPAC传统名: tigecycline hydrate
• 别名: Tygacil; Tigecyclin; TBG-MINO; 9-t-Butylglycylamido-minocycline hydrate

产品登记号

• CAS号: 1229002-07-6

产品性质

• Empirical Formula (Hill Notation): C29H39N5O8 · xH2O
• 纯度: ≥98% (HPLC)
• 外观: off-white to yellow-brown powder
• 比旋光度: [α]/D -160 to 170°, c = 0.15 in methanol
• 溶解度: DMSO: ≥3 mg/mL (warmed)
• GHS警示词: Danger
• GHS危险声明: H319-H360
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P201-P305 + P351 + P338-P308 + P313
• 危险公开号: 61-36-52-64
• RTECS编号: QI7619500
• 安全公开号: 13-36/37/39
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Other Notes
air sensitive
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Tigecycline is a broad spectrum glycylcycline antibiotic. Tigecycline is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline is active against resistant strains of gram-positive and gram-negative bacteria, avoiding the two most common mechanisms of resistance to the tetracycline antimicrobials: tetracycline efflux pump proteins and ribosomal protection proteins.

详细说明 (简体中文)

Other Notes
air sensitive
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Tigecycline is a broad spectrum glycylcycline antibiotic. Tigecycline is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline is active against resistant strains of gram-positive and gram-negative bacteria, avoiding the two most common mechanisms of resistance to the tetracycline antimicrobials: tetracycline efflux pump proteins and ribosomal protection proteins.