Biochem/physiol Actions Farnesyl pyrophosphate is a key intermediate in the biosynthesis of more complex sesquiterpenoids, higher terpenoids, and steroids1 and different biological functions have been discovered for FPP and the corresponding alcohol farnesol2,3,4,5,6,7. FPP plays an important role in the posttranslational processing of Ras proteins. Mutated forms of Ras are associated with human cancer and are therefore investigated in cancer research5,6. |
Biochem/physiol Actions Farnesyl pyrophosphate is a key intermediate in the biosynthesis of more complex sesquiterpenoids, higher terpenoids, and steroids1 and different biological functions have been discovered for FPP and the corresponding alcohol farnesol2,3,4,5,6,7. FPP plays an important role in the posttranslational processing of Ras proteins. Mutated forms of Ras are associated with human cancer and are therefore investigated in cancer research5,6. |